Serologic Response to Cell Wall Mannoproteins and Proteins of Candida albicans

Serologic response to cell wall mannoproteins and proteins of Candida albicans.

The cell wall of Candida albicans not only is the structure in which many biological functions essential for the fungal cells reside but also is a significant source of candidal antigens. The major cell wall components that elicit a response from the host immune system are proteins and glycoproteins, the latter being predominantly mannoproteins. Both the carbohydrate and protein moieties are ab...

Candida albicans and Proteins of Serologic Response to Cell Wall Mannoproteins

Candida albicans cell wall proteins.

The Candida albicans cell wall maintains the structural integrity of the organism in addition to providing a physical contact interface with the environment. The major components of the cell wall are fibrillar polysaccharides and proteins. The proteins of the cell wall are the focus of this review. Three classes of proteins are present in the candidal cell wall. One group of proteins attach to ...

Comparison of cell wall proteins in putative Candida albicans & Candida dubliniensis by using modified staining method & SDSPAGE

 Background: Candida species are among the most common causes of opportunistic fungal diseases. Among Candida species, Candida albicans is responsible for most infections. Having many strains, C. albicans is very polymorph. C. dubliniensis is very similar to albicans species both morphologically and physiologically. For an infection to occur, cell wall proteins play an important role as they en...

Wall formation by Candida albicans yeast cells: synthesis, secretion and incorporation of two types of mannoproteins.

The mannoprotein components solubilized from the walls of Candida albicans blastoconidia following degradation of the glucan network with beta-glucanase (Zymolyase) have higher molecular masses than their probable precursors present in the supernatant of regenerating protoplasts. It therefore appears that the mannoproteins are released from the walls as part of supramolecular complexes. Immunol...